{"product_id":"cjc-1295no-dac","title":"CJC-1295(NO DAC)","description":"\u003cdiv data-docx-has-block-data=\"false\" data-lark-html-role=\"root\" data-page-id=\"Xonnf5No3dPIOUcFDXQcOERMn9e\"\u003e\n\u003cdiv class=\"ace-line ace-line old-record-id-W1VafZrlYd4HdQca7xCc7wu2nNd\"\u003e\n\u003cstrong\u003eCJC-1295 (NO DAC):\u003c\/strong\u003e A Concise Scientific Introduction\u003c\/div\u003e\n\u003cdiv class=\"ace-line ace-line old-record-id-ARGdf4jn8dT6F4cjC2wcVpjfnOd\"\u003e\n\u003cstrong\u003eFull Name: \u003c\/strong\u003eCJC-1295 without Drug Affinity Complex (DAC)\u003c\/div\u003e\n\u003cdiv class=\"ace-line ace-line old-record-id-C69DflMHYdVoAKc337EcOA5cntf\"\u003e\n\u003cstrong\u003eCommon Names: \u003c\/strong\u003eCJC-1295 (NO DAC), Mod GRF 1-29, Tetrasubstituted GRF (1-29)\u003c\/div\u003e\n\u003cdiv class=\"ace-line ace-line old-record-id-LVQZfNM19dgK5Ncw2XcccPCenob\"\u003e\n\u003cstrong\u003eMolecular Formula: \u003c\/strong\u003eC₁₅₂H₂₅₂N₄₄O₄₂\u003c\/div\u003e\n\u003cdiv class=\"ace-line ace-line old-record-id-KSqzfFI5Adv1SbcfW3vc3ZqInjH\"\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 3367.9 g\/mol\u003c\/div\u003e\n\u003cdiv class=\"ace-line ace-line old-record-id-KSqzfFI5Adv1SbcfW3vc3ZqInjH\"\u003e\u003c\/div\u003e\n\u003cdiv class=\"ace-line ace-line old-record-id-P9Z9f4P2QdGTT8cWsiicsku2nYc\"\u003e\n\u003cstrong\u003eResearch Progress: \u003c\/strong\u003eFirst discovered in the early 1980s, CJC-1295 (NO DAC) is a synthetic variant of the naturally occurring Growth Hormone-Releasing Hormone (GHRH). It is a 29-amino-acid peptide modified by four amino acid substitutions to enhance stability and resist degradation by enzymes like dipeptidyl peptidase-4 (DPP-4). In recent years (2025-2026), it has been widely used in research, often combined with other peptides such as Ipamorelin and Sermorelin in blends to explore growth hormone axis modulation, metabolic pathways, and age-related metabolic changes. It is commonly available in lyophilized powder and nasal spray forms, with purity levels typically ≥99% for research use.\u003c\/div\u003e\n\u003cdiv class=\"ace-line ace-line old-record-id-N2sXfiCFad5jx7cqdBOcFcXBnhf\"\u003e\n\u003cstrong\u003eBiological Mechanism of Action:\u003c\/strong\u003e CJC-1295 (NO DAC) primarily acts by mimicking the function of natural GHRH, selectively binding to GHRH receptors on the anterior pituitary gland. This binding triggers intracellular signaling cascades, promoting the pulsatile release of Growth Hormone (GH) — a pattern that closely resembles the body’s natural GH secretion rhythm. Unlike CJC-1295 with DAC, it does not contain a drug affinity complex, resulting in a shorter half-life and acute effects on GH secretion. Elevated GH levels induced by this peptide further regulate physiological processes including muscle growth, lipolysis (fat breakdown), tissue repair, and metabolic health, making it a valuable tool for researching endocrine dynamics and body composition.\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"xprimepeptide.com","offers":[{"title":"2mg*10vials","offer_id":42653980622925,"sku":null,"price":55.0,"currency_code":"USD","in_stock":true},{"title":"5mg*10vials","offer_id":42653980655693,"sku":null,"price":80.0,"currency_code":"USD","in_stock":true},{"title":"10mg*10vials","offer_id":42653980688461,"sku":null,"price":130.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0689\/5049\/1213\/files\/cjc1295_no_dac_10mg.png?v=1770389549","url":"https:\/\/xprimepeptide.com\/products\/cjc-1295no-dac","provider":"xprimepeptide.com","version":"1.0","type":"link"}