{"product_id":"tb500","title":"TB500","description":"\u003cdiv data-page-id=\"HMW1fknrsdCcBgcaMpDctOmhngh\" data-lark-html-role=\"root\" data-docx-has-block-data=\"false\"\u003e\n\u003cdiv class=\"ace-line ace-line old-record-id-YpoYf4JfHd9j2ncEWoWci2eUnce\"\u003eTB500, short for Thymosin Beta-4, is a synthetic peptide analog of the endogenous protein thymosin beta-4, which is naturally present in nearly all mammalian cells. Its molecular formula is C212H350N56O78S, with a molar mass of 4963.44 and CAS number 77591-33-4. It is a 43-amino-acid peptide that plays a key role in tissue repair and wound healing.\u003c\/div\u003e\n\u003cdiv class=\"ace-line ace-line old-record-id-PxpHf1sPGdDBQucUdWpchwv7nXb\"\u003eIn scientific research, TB500 has been extensively studied for its biological activities. Preclinical in vitro studies have shown that TB500 (15-25 μg\/ml) can promote cell migration and wound healing by enhancing ATP-induced intracellular calcium ion increase and activating purinergic P2 receptors. In vivo experiments on BALB\/c mouse skin wound models have demonstrated that topical administration of TB500 (15 μg\/30 μl, once daily for 10 days) significantly accelerates wound healing. Additionally, it has been found to be used as a doping agent in horse and greyhound racing due to its tissue repair properties.\u003c\/div\u003e\n\u003cdiv class=\"ace-line ace-line old-record-id-Ox2zfbshvdacnIcKreHcRebgnzh\"\u003eThe biological mechanism of TB500 mainly involves inhibiting the AKT signaling pathway and binding to actin, thereby exerting anti-fibrotic and wound-healing effects. It promotes endothelial cell differentiation, angiogenesis in dermal tissues, keratinocyte migration and collagen deposition, while reducing inflammation. Its active ingredient, Ac-Tβ4 17-23, also prevents apoptosis, promotes cell survival and immunomodulatory activity by stimulating T cell proliferation.\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"xprimepeptide.com","offers":[{"title":"5mg*10vials","offer_id":42653879337037,"sku":null,"price":70.0,"currency_code":"USD","in_stock":true},{"title":"10mg*10vials","offer_id":42653879369805,"sku":null,"price":130.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0689\/5049\/1213\/files\/tb50010mg.png?v=1770387210","url":"https:\/\/xprimepeptide.com\/products\/tb500","provider":"xprimepeptide.com","version":"1.0","type":"link"}