AOD9604 is a specialized peptide fragment derived from human growth hormone, engineered to target adipose tissue metabolism. This research-grade compound is favored by those exploring peptide-based approaches to body composition optimization. AOD9604 works by signaling fat cells to mobilize stored energy while preserving lean muscle tissue, making it a focus of ongoing scientific interest in metabolic research. Ideal for researchers and practitioners seeking premium-quality peptides for investigational purposes. Each batch undergoes rigorous quality verification to ensure purity and consistency.

Full Name: L-phenylalanine, L-tyrosyl-L-leucyl-L-arginyl-L-isoleucyl-L-valyl-L-glutaminyl-L-cysteinyl-L-arginyl-L-seryl-L-valyl-L-α-glutamyl glycyl-L-seryl-L-cysteinyl glycyl-, cyclic (7→14)-disulfide

Common Names: AOD 9604; AOD9604; Fragment 177-191; AOD 9604 acetate; Peptides AOD9604; HGH Frag 176-191 oxidized

Molecular Formula: C78H123N23O23S2

Molecular Weight: 1815.1

Research Progress: AOD9604 is mainly researched for its potential in obesity treatment. By February 2002, Phase IIa clinical trials for obesity treatment were underway. Animal studies have shown it can induce weight loss and increase lipolytic sensitivity in obese mice. It has also been studied in human sports drug testing for its detection methods and metabolism. Current research focuses on its lipolytic mechanism and potential clinical applications, with no obvious serious adverse effects reported in relevant studies.

Biological Mechanism of Action: AOD9604 is a lipolytic fragment derived from the C-terminus of human growth hormone (hGH), retaining hGH’s lipolytic and anti-lipogenic effects. It can increase the expression of β3-adrenergic receptor (β3-AR) RNA in fat cells, thereby enhancing lipolytic sensitivity. Although it does not directly mediate lipolysis through β3-AR, it can promote fat oxidation and energy expenditure. Additionally, it helps reduce body fat mass without affecting normal insulin function, playing a role in regulating lipid metabolism and supporting weight loss.