CJC-1295(with DAC)

CJC-1295(with DAC)

2mg*10vials
$75.00 USD
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CJC-1295(with DAC)
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CJC-1295(with DAC)

$75.00 USD
包装剂量
Description
CJC-1295 (NO DAC): A Concise Scientific Introduction
Full Name: CJC-1295 without Drug Affinity Complex (DAC)
Common Names: CJC-1295 (NO DAC), Mod GRF 1-29, Tetrasubstituted GRF (1-29)
Molecular Formula: C₁₅₂H₂₅₂N₄₄O₄₂
Molecular Weight: 3367.9 g/mol

Research Progress: First discovered in the early 1980s, CJC-1295 (NO DAC) is a synthetic variant of the naturally occurring Growth Hormone-Releasing Hormone (GHRH). It is a 29-amino-acid peptide modified by four amino acid substitutions to enhance stability and resist degradation by enzymes like dipeptidyl peptidase-4 (DPP-4). In recent years (2025-2026), it has been widely used in research, often combined with other peptides such as Ipamorelin and Sermorelin in blends to explore growth hormone axis modulation, metabolic pathways, and age-related metabolic changes. It is commonly available in lyophilized powder and nasal spray forms, with purity levels typically ≥99% for research use.
Biological Mechanism of Action: CJC-1295 (NO DAC) primarily acts by mimicking the function of natural GHRH, selectively binding to GHRH receptors on the anterior pituitary gland. This binding triggers intracellular signaling cascades, promoting the pulsatile release of Growth Hormone (GH) — a pattern that closely resembles the body’s natural GH secretion rhythm. Unlike CJC-1295 with DAC, it does not contain a drug affinity complex, resulting in a shorter half-life and acute effects on GH secretion. Elevated GH levels induced by this peptide further regulate physiological processes including muscle growth, lipolysis (fat breakdown), tissue repair, and metabolic health, making it a valuable tool for researching endocrine dynamics and body composition.

 

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