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Semaglutide (SM)
$60.00 USD
Description
Semaglutide (SM) is a long-acting glucagon-like peptide-1 (GLP-1) receptor agonist, artificially modified based on the human endogenous GLP-1 sequence. This research-grade bioactive compound is widely studied in metabolic regulation and body weight management research fields. Semaglutide works by simulating the physiological activity of endogenous GLP-1, regulating blood glucose metabolism and suppressing appetite, while improving energy metabolism balance, making it a core research hotspot in metabolic and endocrinology studies. Ideal for researchers and medical practitioners conducting investigational experiments on glycemic regulation and obesity intervention. Each batch is subjected to strict standardized quality testing to guarantee high purity, stable composition and consistent experimental repeatability.
Full Name: N6-(17-carboxyheptadecanoyl)-L-alanyl-L-glutaminyl-L-glycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-glutaminyl-L-alanyl-L-alanyl-L-lysyl-L-glutamyl-L-valyl-L-leucyl-L-tryptophyl-L-leucyl-L-arginyl-L-glycyl-glycine
Common Names: Semaglutide; SM; GLP-1 Receptor Agonist; Semaglutide raw peptide; Long-acting GLP-1 analogue
Molecular Formula: C187H291N45O59
Molecular Weight: 4113.6
Research Progress: Semaglutide is primarily researched for its therapeutic potential in type 2 diabetes mellitus and chronic obesity. Relevant phase II and phase III clinical trials have been successively completed and verified, with stable efficacy confirmed in human clinical studies. Preclinical animal experiments have proven that it can effectively reduce body weight, improve glucose tolerance and reduce visceral fat accumulation in obese and hyperglycemic model animals. It is also extensively studied in metabolic syndrome intervention, cardiovascular risk improvement and related pharmacological metabolism research. Current research focuses on its long-term metabolic regulation mechanism, dose-effect relationship and expanded clinical application scenarios, with mild and tolerable adverse reactions observed in mainstream studies and no severe safety risks confirmed.
Biological Mechanism of Action: Semaglutide is a modified long-acting GLP-1 receptor agonist with high affinity for human GLP-1 receptors. It can activate downstream signaling pathways after binding to GLP-1 receptors, significantly promoting glucose-dependent insulin secretion and inhibiting abnormal glucagon secretion. It delays gastric emptying to reduce excessive food intake and suppress central nervous system appetite signals, thereby reducing calorie intake. In addition, it improves peripheral insulin sensitivity, accelerates sugar and lipid metabolism, and reduces fat deposition in the body. It stably regulates glycolipid metabolism, achieves sustained weight loss and blood glucose stabilization, and does not cause abnormal blood glucose fluctuations under normal physiological conditions.
Care
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