Tirzepatide(TR) TR Peptide Glycolipid Regulation Weight Management

Tirzepatide (TR) is a novel dual-target incretin receptor agonist artificially optimized based on endogenous gastrointestinal hormone sequences. This research-grade bioactive peptide is highly valued in academic research focusing on glycolipid metabolism and body composition regulation. Tirzepatide functions by activating both GLP-1 and GIP receptors in the human body, synergistically regulating energy metabolism and reducing fat accumulation while preserving basic metabolic stability, making it a cutting-edge subject in current metabolic pharmacology research. Suitable for scientific researchers and industry practitioners engaged in metabolic intervention and weight management investigational studies. Every batch undergoes comprehensive quality inspection and purification procedures to ensure high purity, structural stability and experimental consistency.

Full Name: N-(20-carboxyeicosanoyl)-L-alanyl-L-glutaminyl-L-glycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-glutaminyl-L-alanyl-L-alanyl-L-lysyl-L-glutamyl-L-valyl-L-leucyl-L-tryptophyl-L-leucyl-L-arginyl-L-glycyl-glycine

Common Names: Tirzepatide; TR; Dual GLP-1/GIP Agonist; Tirzepatide raw peptide; Mounjaro peptide

Molecular Formula: C225H348N48O67

Molecular Weight: 4812.5

Research Progress: Tirzepatide is mainly investigated for its potent therapeutic effects on type 2 diabetes and refractory obesity. Multiple phase II and phase III clinical trials have been completed to validate its efficacy in human subjects. Animal model studies have demonstrated its outstanding performance in reducing body weight, lowering blood glucose levels and improving metabolic disorders in obese and diabetic experimental animals. It is also widely explored in research related to non-alcoholic fatty liver disease, metabolic syndrome and cardiovascular metabolic protection. Current studies focus on its dual-receptor synergistic mechanism and long-term metabolic regulatory effects, with only mild gastrointestinal adverse reactions reported and no significant severe toxic side effects found in existing clinical and preclinical data.

Biological Mechanism of Action: Tirzepatide is a unique dual GLP-1/GIP receptor agonist with high biological activity and long half-life characteristics. It exerts dual metabolic regulation effects by simultaneously activating glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide receptors. It enhances glucose-stimulated insulin secretion, suppresses glucagon over-secretion, and delays gastric emptying to curb excessive calorie intake. Different from single-target GLP-1 agonists, it further optimizes energy expenditure through GIP pathway activation, significantly improving lipolysis efficiency and inhibiting de novo lipogenesis. Furthermore, it improves whole-body insulin sensitivity, stably regulates glycolipid homeostasis, and achieves efficient body fat reduction without disrupting normal physiological metabolic functions.

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